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CIK 0001658551 · Non-accelerated filer<br>Smaller reporting company

Amylyx Pharmaceuticals, Inc.

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Ticker
AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
FY end
Dec 31
Incorporated
DE
Entity type
operating
EIN
464600503
Phone
617-682-0917
Business address
55 CAMBRIDGE PARKWAY, SUITE 6W, CAMBRIDGE, MA, 02142
Open-market buys, last 90 days
$0
in 0 filings
Open-market sales, last 90 days
$3,775,866
in 6 filings, $831K under 10b5-1 plans

Net −$3,775,866. Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Pace of trading Bought Sold

Who's trading

90 days

  1. Cohen Joshua B −$981K Co-Chief Executive Officer sold <1% of stake
  2. Klee Justin B. −$980K Co-Chief Executive Officer sold <1% of stake
  3. MILNE GEORGE M JR −$831K Director sold 4% of stake
  4. FRATES JAMES M −$350K Chief Financial Officer sold 4% of stake
  5. Bedrosian Camille L −$325K Chief Medical Officer sold 3% of stake
Date Insider Transaction Shares Price Value Owned after
2026-10-05 MILNE GEORGE M JR Director Sale 10b5-1 −30,000 $27.70 $831K 782,881
2026-09-10 Bedrosian Camille L Chief Medical Officer Sale −7,947 $32.21 $256K 280,145
2026-09-10 Bedrosian Camille L Chief Medical Officer Sale −2,081 $33.09 $69K 278,064
2026-09-10 FRATES JAMES M Chief Financial Officer Sale −9,768 $32.27 $315K 234,667
2026-09-10 FRATES JAMES M Chief Financial Officer Sale −1,042 $33.23 $35K 233,625
2026-09-10 Mazzariello Gina Chief Legal Officer Sale −9,525 $32.46 $309K 190,849
2026-09-10 Mazzariello Gina Chief Legal Officer Sale −11 $33.34 $367 190,838
2026-09-10 Cohen Joshua B Co-Chief Executive Officer Sale −29,545 $32.16 $950K 3,614,042
2026-09-10 Cohen Joshua B Co-Chief Executive Officer Sale −919 $33.15 $30K 3,613,123
2026-09-10 Klee Justin B. Co-Chief Executive Officer Sale −29,025 $32.13 $933K 3,614,495
2026-09-10 Klee Justin B. Co-Chief Executive Officer Sale −1,439 $33.16 $48K 3,613,056
2026-08-31 Firestone Karen Director Option exercise +25,000 $1.76 $44K 91,900
2026-08-31 Firestone Karen Director Option exercise +25,000 $5.05 $126K 116,900
2026-08-31 Firestone Karen Director Option exercise · Stock Option (right to buy) −25,000 0
2026-08-31 Firestone Karen Director Option exercise · Stock Option (right to buy) −25,000 0
2026-08-18 FRATES JAMES M Chief Financial Officer Grant or award +22,807 244,435
2026-08-18 Klee Justin B. Co-Chief Executive Officer Grant or award +60,039 3,643,520
2026-08-18 Mazzariello Gina Chief Legal Officer Grant or award +21,284 200,374
2026-08-18 Bedrosian Camille L Chief Medical Officer Grant or award +22,807 288,092
2026-08-18 Cohen Joshua B Co-Chief Executive Officer Grant or award +60,039 3,643,587

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