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CIK 0001658551 · Non-accelerated filer<br>Smaller reporting company

Amylyx Pharmaceuticals, Inc.

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Ticker
AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
FY end
Dec 31
Incorporated
DE
Entity type
operating
EIN
464600503
Phone
617-682-0917
Business address
55 CAMBRIDGE PARKWAY, SUITE 6W, CAMBRIDGE, MA, 02142
Open-market buys, last 90 days
$0
in 0 filings
Open-market sales, last 90 days
$10,951,125
in 9 filings, $8.0M under 10b5-1 plans

Net −$10,951,125. Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Pace of trading Bought Sold

Who's trading

90 days

  1. Cohen Joshua B −$4.0M Co-Chief Executive Officer sold 4% of stake
  2. Klee Justin B. −$4.0M Co-Chief Executive Officer sold 4% of stake
  3. FRATES JAMES M −$1.6M Chief Financial Officer sold 18% of stake
  4. MILNE GEORGE M JR −$831K Director sold 4% of stake
  5. Bedrosian Camille L −$325K Chief Medical Officer sold 3% of stake
Date Insider Transaction Shares Price Value Owned after
2026-01-16 Cohen Joshua B Co-Chief Executive Officer Option exercise +2,818 $7.57 $21K 3,381,439
2026-01-16 Cohen Joshua B Co-Chief Executive Officer Sale −1,974 $13.83 $27K 3,379,465
2026-01-16 Cohen Joshua B Co-Chief Executive Officer Option exercise · Stock Option (Right to Buy) −2,818 0
2026-01-16 Klee Justin B. Co-Chief Executive Officer Option exercise +2,847 $7.57 $22K 3,381,393
2026-01-16 Klee Justin B. Co-Chief Executive Officer Sale −1,995 $13.89 $28K 3,379,398
2026-01-16 Klee Justin B. Co-Chief Executive Officer Option exercise · Stock Option (Right to Buy) −2,847 0
2026-01-15 Cohen Joshua B Co-Chief Executive Officer Option exercise +197,182 $7.57 $1.5M 3,514,814
2026-01-15 Cohen Joshua B Co-Chief Executive Officer Sale −136,193 $13.59 $1.9M 3,378,621
2026-01-15 Cohen Joshua B Co-Chief Executive Officer Option exercise · Stock Option (Right to Buy) −197,182 2,818
2026-01-15 Klee Justin B. Co-Chief Executive Officer Option exercise +197,153 $7.57 $1.5M 3,514,739
2026-01-15 Klee Justin B. Co-Chief Executive Officer Sale −136,193 $13.58 $1.8M 3,378,546
2026-01-15 Klee Justin B. Co-Chief Executive Officer Option exercise · Stock Option (Right to Buy) −197,153 2,847
2026-01-12 MILNE GEORGE M JR Director Gift −17,780 812,881
2026-01-06 FRATES JAMES M Chief Financial Officer Sale −3,326 $11.11 $37K 177,104
2026-01-06 Cohen Joshua B Co-Chief Executive Officer Sale −7,715 $11.09 $86K 3,317,632
2026-01-06 Klee Justin B. Co-Chief Executive Officer Sale −7,715 $11.09 $86K 3,317,586
2025-12-23 Firestone Karen Director Purchase +8,100 $12.45 $101K 63,100
2025-12-01 Bedrosian Camille L Chief Medical Officer Sale −6,580 $14.35 $94K 175,756
2025-09-30 Klee Justin B. Co-Chief Executive Officer Sale −29,775 $14.37 $428K 3,325,501
2025-09-30 Klee Justin B. Co-Chief Executive Officer Sale −200 $15.01 $3K 3,325,301

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