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CIK 0001658551 · Non-accelerated filer<br>Smaller reporting company

Amylyx Pharmaceuticals, Inc.

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Ticker
AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
FY end
Dec 31
Incorporated
DE
Entity type
operating
EIN
464600503
Phone
617-682-0917
Business address
55 CAMBRIDGE PARKWAY, SUITE 6W, CAMBRIDGE, MA, 02142
Open-market buys, last 90 days
$0
in 0 filings
Open-market sales, last 90 days
$10,951,125
in 9 filings, $8.0M under 10b5-1 plans

Net −$10,951,125. Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Pace of trading Bought Sold

Who's trading

90 days

  1. Cohen Joshua B −$4.0M Co-Chief Executive Officer sold 4% of stake
  2. Klee Justin B. −$4.0M Co-Chief Executive Officer sold 4% of stake
  3. FRATES JAMES M −$1.6M Chief Financial Officer sold 18% of stake
  4. MILNE GEORGE M JR −$831K Director sold 4% of stake
  5. Bedrosian Camille L −$325K Chief Medical Officer sold 3% of stake
Date Insider Transaction Shares Price Value Owned after
2026-03-05 Cohen Joshua B Co-Chief Executive Officer Grant or award +248,865 3,583,548
2026-03-05 Cohen Joshua B Co-Chief Executive Officer Grant or award · Stock Option (Right to Buy) +373,295 373,295
2026-03-05 Mazzariello Gina Chief Legal Officer Grant or award +74,660 209,090
2026-03-05 Mazzariello Gina Chief Legal Officer Grant or award · Stock Option (Right to Buy) +111,990 111,990
2026-03-05 FRATES JAMES M Chief Financial Officer Grant or award +95,990 261,628
2026-03-05 FRATES JAMES M Chief Financial Officer Grant or award · Stock Option (right to buy) +143,985 143,985
2026-03-05 Klee Justin B. Co-Chief Executive Officer Grant or award +248,865 3,583,481
2026-03-05 Klee Justin B. Co-Chief Executive Officer Grant or award · Stock Option (Right to Buy) +373,295 373,295
2026-03-05 Bedrosian Camille L Chief Medical Officer Grant or award +95,990 265,285
2026-03-05 Bedrosian Camille L Chief Medical Officer Grant or award · Stock Option (Right to Buy) +143,985 143,985
2026-03-02 Klee Justin B. Co-Chief Executive Officer Sale −29,282 $14.47 $424K 3,334,616
2026-03-02 Cohen Joshua B Co-Chief Executive Officer Sale −29,282 $14.48 $424K 3,334,683
2026-03-02 Bedrosian Camille L Chief Medical Officer Sale −6,461 $14.58 $94K 169,295
2026-03-02 FRATES JAMES M Chief Financial Officer Sale −7,909 $14.52 $115K 165,638
2026-03-02 Mazzariello Gina Chief Legal Officer Sale −6,844 $14.52 $99K 134,430
2026-02-23 Mazzariello Gina Chief Legal Officer Sale −3,419 $14.14 $48K 141,274
2026-02-02 FRATES JAMES M Chief Financial Officer Sale −3,557 $14.65 $52K 173,547
2026-02-02 Cohen Joshua B Co-Chief Executive Officer Sale −15,500 $14.68 $228K 3,363,965
2026-02-02 Mazzariello Gina Chief Legal Officer Sale −3,448 $14.65 $51K 144,693
2026-02-02 Klee Justin B. Co-Chief Executive Officer Sale −15,500 $14.69 $228K 3,363,898

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