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CIK 0001658551 · Non-accelerated filer<br>Smaller reporting company

Amylyx Pharmaceuticals, Inc.

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Ticker
AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
FY end
Dec 31
Incorporated
DE
Entity type
operating
EIN
464600503
Phone
617-682-0917
Business address
55 CAMBRIDGE PARKWAY, SUITE 6W, CAMBRIDGE, MA, 02142
Open-market buys, last 90 days
$0
in 0 filings
Open-market sales, last 90 days
$10,951,125
in 9 filings, $8.0M under 10b5-1 plans

Net −$10,951,125. Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Date Insider Transaction Shares Price Value Owned after
2026-09-10 Cohen Joshua B Co-Chief Executive Officer Sale −919 $33.15 $30K 3,613,123
2026-09-10 Klee Justin B. Co-Chief Executive Officer Sale −29,025 $32.13 $933K 3,614,495
2026-09-10 Klee Justin B. Co-Chief Executive Officer Sale −1,439 $33.16 $48K 3,613,056
2026-08-31 Firestone Karen Director Option exercise +25,000 $1.76 $44K 91,900
2026-08-31 Firestone Karen Director Option exercise +25,000 $5.05 $126K 116,900
2026-08-31 Firestone Karen Director Option exercise · Stock Option (right to buy) −25,000 0
2026-08-31 Firestone Karen Director Option exercise · Stock Option (right to buy) −25,000 0
2026-08-18 FRATES JAMES M Chief Financial Officer Grant or award +22,807 244,435
2026-08-18 Klee Justin B. Co-Chief Executive Officer Grant or award +60,039 3,643,520
2026-08-18 Mazzariello Gina Chief Legal Officer Grant or award +21,284 200,374
2026-08-18 Bedrosian Camille L Chief Medical Officer Grant or award +22,807 288,092
2026-08-18 Cohen Joshua B Co-Chief Executive Officer Grant or award +60,039 3,643,587
2026-07-10 Mazzariello Gina Chief Legal Officer Sale 10b5-1 −15,000 $17.61 $264K 179,090
2026-07-09 Mazzariello Gina Chief Legal Officer Sale 10b5-1 −15,000 $18.32 $275K 194,090
2026-06-04 Zeiher Bernhardt G Director Grant or award · Stock Option (right to buy) +24,372 24,372
2026-06-04 Firestone Karen Director Grant or award · Stock Option (right to buy) +24,372 24,372
2026-06-04 Quimi Daphne Director Grant or award · Stock Option (right to buy) +24,372 24,372
2026-06-04 MILNE GEORGE M JR Director Grant or award · Stock Option (right to buy) +24,372 24,372
2026-06-04 FONTEYNE PAUL R. Director Grant or award · Stock Option (right to buy) +24,372 24,372
2026-05-21 Firestone Karen Director Purchase +3,800 $13.51 $51K 66,900

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