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CIK 0001658551 · Non-accelerated filer<br>Smaller reporting company

Amylyx Pharmaceuticals, Inc.

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Ticker
AMLX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
FY end
Dec 31
Incorporated
DE
Entity type
operating
EIN
464600503
Phone
617-682-0917
Business address
55 CAMBRIDGE PARKWAY, SUITE 6W, CAMBRIDGE, MA, 02142
Open-market buys, last 90 days
$0
in 0 filings
Open-market sales, last 90 days
$10,951,125
in 9 filings, $8.0M under 10b5-1 plans

Net −$10,951,125. Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Date Insider Transaction Shares Price Value Owned after
2026-11-10 FRATES JAMES M Chief Financial Officer Option exercise 10b5-1 +20,000 $6.88 $138K 253,625
2026-11-10 FRATES JAMES M Chief Financial Officer Sale 10b5-1 −12,800 $30.32 $388K 240,825
2026-11-10 FRATES JAMES M Chief Financial Officer Sale 10b5-1 −7,200 $30.97 $223K 233,625
2026-11-10 FRATES JAMES M Chief Financial Officer Option exercise · Stock Option (right to buy) 10b5-1 −20,000 323,835
2026-11-09 FRATES JAMES M Chief Financial Officer Option exercise 10b5-1 +20,000 $6.88 $138K 253,625
2026-11-09 FRATES JAMES M Chief Financial Officer Sale 10b5-1 −7,700 $29.39 $226K 245,925
2026-11-09 FRATES JAMES M Chief Financial Officer Sale 10b5-1 −12,300 $30.11 $370K 233,625
2026-11-09 FRATES JAMES M Chief Financial Officer Option exercise · Stock Option (right to buy) 10b5-1 −20,000 343,835
2026-09-10 FRATES JAMES M Chief Financial Officer Sale −9,768 $32.27 $315K 234,667
2026-09-10 FRATES JAMES M Chief Financial Officer Sale −1,042 $33.23 $35K 233,625
2026-08-18 FRATES JAMES M Chief Financial Officer Grant or award +22,807 244,435
2026-03-05 FRATES JAMES M Chief Financial Officer Grant or award +95,990 261,628
2026-03-05 FRATES JAMES M Chief Financial Officer Grant or award · Stock Option (right to buy) +143,985 143,985
2026-03-02 FRATES JAMES M Chief Financial Officer Sale −7,909 $14.52 $115K 165,638
2026-02-02 FRATES JAMES M Chief Financial Officer Sale −3,557 $14.65 $52K 173,547
2026-01-06 FRATES JAMES M Chief Financial Officer Sale −3,326 $11.11 $37K 177,104
2025-09-30 FRATES JAMES M Chief Financial Officer Sale −10,558 $14.65 $155K 280,430
2025-03-31 FRATES JAMES M Chief Financial Officer Sale −10,896 $3.47 $38K 290,988
2025-03-06 FRATES JAMES M Chief Financial Officer Grant or award +68,420 301,884
2025-03-06 FRATES JAMES M Chief Financial Officer Grant or award · Stock Option (right to buy) +102,630 102,630

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