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CIK 0002022626 · Non-accelerated filer<br>Smaller reporting company<br>Emerging growth company

Upstream Bio, Inc.

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Ticker
UPB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
FY end
Dec 31
Incorporated
DE
Entity type
operating
Phone
781-208-2466
Business address
890 WINTER STREET, SUITE 200, WALTHAM, MA, 02451
Open-market buys, last 90 days
$0
in 0 filings
Open-market sales, last 90 days
$27,604
in 5 filings

Net −$27,604. Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Date Insider Transaction Shares Price Value Owned after
2024-10-15 ORBIMED ADVISORS LLC Director Conversion · Series A redeemable convertible preferred stock −524,500 0
2024-10-15 ORBIMED ADVISORS LLC Director Conversion · Series A redeemable convertible preferred stock −2,098,000 0
2024-10-15 ORBIMED ADVISORS LLC Director Conversion · Series B redeemable convertible preferred stock −197,456 0
2024-10-15 ORBIMED ADVISORS LLC Director Conversion · Series B redeemable convertible preferred stock −789,833 0
2024-10-15 Wellington Biomedical Innovation Master Investors (Cayman) II L.P. 10% owner Conversion +894,733 894,733
2024-10-15 Wellington Biomedical Innovation Master Investors (Cayman) II L.P. 10% owner Conversion · Series B redeemable convertible preferred stock −852,940 0
2024-10-10 Renaud Ronald C JR Director Grant or award · Stock Option (Right to Buy) +17,096 17,096
2024-10-10 Beckman Daniella Director Grant or award · Stock Option (Right to Buy) +34,681 34,681
2024-10-10 Chimovits Erez Director Grant or award · Stock Option (Right to Buy) +17,096 17,096
2024-10-10 Ruddy Marcella K. Director Grant or award · Stock Option (Right to Buy) +17,096 17,096
2024-10-10 Fleming Harold Edward Director Grant or award · Stock Option (Right to Buy) +17,096 17,096
2024-10-10 Ratcliffe Liam Director Grant or award · Stock Option (Right to Buy) +17,096 17,096

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