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CIK 0001683553 · Non-accelerated filer<br>Smaller reporting company

SPRUCE BIOSCIENCES, INC.

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Ticker
SPRB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
FY end
Dec 31
Incorporated
DE
Entity type
operating
EIN
812154263
Phone
(415) 655-4168
Business address
611 GATEWAY BOULEVARD, SUITE 740, SOUTH SAN FRANCISCO, CA, 94080
Open-market buys, last 90 days
$0
in 0 filings
Open-market sales, last 90 days
$0
in 0 filings

Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Reading 12 more Form 4s from the SEC; this list fills in as they're read.

Date Insider Transaction Shares Price Value Owned after
2025-10-06 Parkman Healthcare Partners LLC 10% owner Sale −25 $17.46 $436 1,050
2025-07-23 Ways Kirk Interim Chief Medical Officer Grant or award · Stock Option (Right to Buy) +30,000 30,000
2025-07-22 SPIEGELMAN DANIEL K Director Grant or award · Stock Option (Right to Buy) +30,000 30,000
2025-07-22 SIMPSON CAMILLA V Director Grant or award · Stock Option (Right to Buy) +30,000 30,000
2025-07-22 GREY MICHAEL G Executive Chairman Grant or award · Stock Option (Right to Buy) +30,000 30,000
2025-07-22 Barretto-Ko Percival Director Grant or award · Stock Option (Right to Buy) +30,000 30,000
2025-07-22 Aynechi Tiba Director Grant or award · Stock Option (Right to Buy) +30,000 30,000
2025-07-22 Muralidhar Bali Director Grant or award · Stock Option (Right to Buy) +30,000 30,000
2024-12-16 Charlton Ralph William III CHIEF MEDICAL OFFICER Option exercise +26,600 150,409
2024-12-16 Charlton Ralph William III CHIEF MEDICAL OFFICER Shares withheld for taxes −9,491 $0.39 $4K 140,918
2024-12-16 Charlton Ralph William III CHIEF MEDICAL OFFICER Option exercise +31,750 172,668
2024-12-16 Charlton Ralph William III CHIEF MEDICAL OFFICER Shares withheld for taxes −11,329 $0.39 $4K 161,339
2024-12-16 Charlton Ralph William III CHIEF MEDICAL OFFICER Option exercise · Restricted Stock Units −26,600 79,800
2024-12-16 Charlton Ralph William III CHIEF MEDICAL OFFICER Option exercise · Restricted Stock Units −31,750 63,500
2024-12-16 Gharib Samir M. PRESIDENT AND CFO Option exercise +38,500 340,328
2024-12-16 Gharib Samir M. PRESIDENT AND CFO Shares withheld for taxes −13,737 $0.39 $5K 326,591
2024-12-16 Gharib Samir M. PRESIDENT AND CFO Option exercise +37,250 363,841
2024-12-16 Gharib Samir M. PRESIDENT AND CFO Shares withheld for taxes −13,291 $0.39 $5K 350,550
2024-12-16 Gharib Samir M. PRESIDENT AND CFO Option exercise · Restricted Stock Units −38,500 115,500
2024-12-16 Gharib Samir M. PRESIDENT AND CFO Option exercise · Restricted Stock Units −37,250 74,500

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