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CIK 0001683553 · Non-accelerated filer<br>Smaller reporting company

SPRUCE BIOSCIENCES, INC.

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Ticker
SPRB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
FY end
Dec 31
Incorporated
DE
Entity type
operating
EIN
812154263
Phone
(415) 655-4168
Business address
611 GATEWAY BOULEVARD, SUITE 740, SOUTH SAN FRANCISCO, CA, 94080
Open-market buys, last 90 days
$0
in 0 filings
Open-market sales, last 90 days
$0
in 0 filings

Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Reading 12 more Form 4s from the SEC; this list fills in as they're read.

Date Insider Transaction Shares Price Value Owned after
2025-12-11 GREY MICHAEL G Executive Chairman Returned to the company · Stock Option (Right to Buy) −1,499 0
2025-12-11 GREY MICHAEL G Executive Chairman Grant or award · Stock Option (right to buy) +133 133
2025-12-11 GREY MICHAEL G Executive Chairman Returned to the company · Stock Option (right to buy) −133 0
2025-12-11 GREY MICHAEL G Executive Chairman Grant or award · Stock Option (Right to Buy) +666 666
2025-12-11 GREY MICHAEL G Executive Chairman Returned to the company · Stock Option (Right to Buy) −666 0
2025-12-11 GREY MICHAEL G Executive Chairman Grant or award · Stock Option (Right to Buy) +400 400
2025-12-11 GREY MICHAEL G Executive Chairman Returned to the company · Stock Option (Right to Buy) −400 0
2025-12-11 SPIEGELMAN DANIEL K Director Grant or award · Stock Option (Right to Buy) +458 458
2025-12-11 SPIEGELMAN DANIEL K Director Returned to the company · Stock Option (Right to Buy) −458 0
2025-12-11 SPIEGELMAN DANIEL K Director Grant or award · Stock Option (right to buy) +88 88
2025-12-11 SPIEGELMAN DANIEL K Director Returned to the company · Stock Option (right to buy) −88 0
2025-12-11 SPIEGELMAN DANIEL K Director Grant or award · Stock Option (Right to Buy) +400 400
2025-12-11 SPIEGELMAN DANIEL K Director Returned to the company · Stock Option (Right to Buy) −400 0
2025-12-11 Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER Option exercise +4,950 15,192
2025-12-11 Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER Shares withheld for taxes −2,194 $88.41 $194K 12,998
2025-12-11 Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER Grant or award · Restricted Stock Units +19,800 19,800
2025-12-11 Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER Option exercise · Restricted Stock Units −4,950 14,850
2025-12-11 Gharib Samir M. PRESIDENT AND CFO Option exercise +1,900 8,296
2025-12-11 Gharib Samir M. PRESIDENT AND CFO Shares withheld for taxes −680 $88.41 $60K 7,616
2025-12-11 Gharib Samir M. PRESIDENT AND CFO Grant or award · Restricted Stock Units +7,600 7,600

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