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CIK 0001984086 · Non-accelerated filer<br>Smaller reporting company<br>Emerging growth company

Septerna, Inc.

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Ticker
SEPN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
FY end
Dec 31
Incorporated
DE
Entity type
operating
EIN
843891440
Phone
650-338-3533
Business address
250 EAST GRAND AVENUE, SUITE 65, SOUTH SAN FRANCISCO, CA, 94080
Open-market buys, last 90 days
$0
in 0 filings
Open-market sales, last 90 days
$4,210,085
in 3 filings, $4.2M under 10b5-1 plans

Net −$4,210,085. Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Date Insider Transaction Shares Price Value Owned after
2026-11-11 Ezekowitz Alan Director Sale 10b5-1 −6,939 $46.01 $319K 110,481
2026-11-11 Ezekowitz Alan Director Sale 10b5-1 −13,201 $47.01 $621K 97,280
2026-11-11 Ezekowitz Alan Director Sale 10b5-1 −22,865 $47.78 $1.1M 74,415
2026-11-11 Ezekowitz Alan Director Sale 10b5-1 −31,572 $48.70 $1.5M 42,843
2026-11-11 Ezekowitz Alan Director Sale 10b5-1 −4,175 $49.65 $207K 38,668
2026-11-11 Ezekowitz Alan Director Sale 10b5-1 −2,013 $50.90 $102K 36,655
2026-11-11 Ezekowitz Alan Director Sale 10b5-1 −1,055 $51.90 $55K 35,600
2026-10-15 Bhatt Elizabeth President and COO Option exercise 10b5-1 +4,000 $6.81 $27K 178,209
2026-10-15 Bhatt Elizabeth President and COO Sale 10b5-1 −1,094 $36.87 $40K 177,115
2026-10-15 Bhatt Elizabeth President and COO Sale 10b5-1 −2,906 $37.61 $109K 174,209
2026-10-15 Bhatt Elizabeth President and COO Option exercise · Stock Option (Right to Buy) 10b5-1 −4,000 58,230
2026-09-08 Patni Rajiv Chief Medical Officer Grant or award · Stock Option (Right to Buy) +275,000 275,000
2026-09-01 Long Daniel D. SVP, Drug Discovery Option exercise 10b5-1 +3,333 $2.76 $9K 99,745
2026-09-01 Long Daniel D. SVP, Drug Discovery Sale 10b5-1 −3,333 $37.83 $126K 96,412
2026-09-01 Long Daniel D. SVP, Drug Discovery Option exercise · Stock Option (Right to Buy) 10b5-1 −3,333 9,085
2026-08-12 RA CAPITAL MANAGEMENT, L.P. Director Sale −746,500 $42.50 $31.7M 4,777,415
2026-08-12 RA CAPITAL MANAGEMENT, L.P. Director Sale −746,500 $42.50 $31.7M 725,443
2026-08-12 Third Rock Ventures V, L.P. 10% owner Sale 10b5-1 +147,059 $50.27 $7.4M 6,068,532
2026-08-12 Third Rock Ventures V, L.P. 10% owner Sale 10b5-1 +141 $51.08 $7K 6,068,391
2026-08-11 Bhatt Elizabeth President and COO Option exercise 10b5-1 +18,681 $6.81 $127K 192,890

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