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CIK 0001814114 · Non-accelerated filer<br>Smaller reporting company

Orchestra BioMed Holdings, Inc.

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Ticker
OBIO
Exchange
Nasdaq
Industry
Surgical & Medical Instruments & Apparatus
FY end
Dec 31
Incorporated
DE
Entity type
operating
Phone
646-343-9298
Business address
150 UNION SQUARE DRIVE, NEW HOPE, PA, 18938
Former names
Health Sciences Acquisitions Corp 2
Open-market buys, last 90 days
$6,288,560
in 7 filings
Open-market sales, last 90 days
$255,600
in 3 filings, $256K under 10b5-1 plans

Net +$6,032,960. Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Pace of trading Bought Sold

Who's trading

90 days

  1. RTW INVESTMENTS, LP +$6.0M 10% owner 1 filing
  2. Sherman Darren −$245K See Remarks sold 4% of stake
  3. Fain Eric S +$100K Director 1 filing
  4. Pacitti David +$100K Director 1 filing
  5. Hochman David P +$73K See Remarks 2 filings
Date Insider Transaction Shares Price Value Owned after
2025-08-07 Aryeh Jason Director Grant or award +15,000 107,482
2025-08-07 Sherman Darren See Remarks Grant or award +120,000 923,837
2025-08-07 Connealy Pamela Ann Director Grant or award +15,000 48,711
2025-08-07 Mack John Prosper Director Grant or award +15,000 40,286
2025-08-07 Fain Eric S Director Grant or award +7,500 7,500
2025-08-07 Fain Eric S Director Grant or award +7,500 58,449
2025-08-07 Cleary Chris Director Grant or award +15,000 37,577
2025-08-07 Hochman David P See Remarks Grant or award +100,000 645,460
2025-08-07 Hochman David P See Remarks Grant or award +100,000 449,331
2025-08-07 Pacitti David Director Grant or award +15,000 44,968
2025-08-07 Aiello Joshua Principal Accounting Officer Grant or award +15,000 19,329
2025-08-04 RTW INVESTMENTS, LP 10% owner Purchase · Pre-Funded Warrants (Right to Buy) +3,636,363 $2.75 $10.0M 3,636,363
2025-08-04 Hochman David P See Remarks Purchase +20,000 $2.75 $55K 349,331
2025-08-01 PERCEPTIVE ADVISORS LLC 10% owner Purchase +700,000 $2.75 $1.9M 5,292,556
2025-08-01 PERCEPTIVE ADVISORS LLC 10% owner Purchase · Pre-funded Warrants (right to buy) +1,500,000 $2.75 $4.1M 1,500,000
2025-06-26 Fain Eric S Director Sale −2,683 $3.05 $8K 50,949
2025-06-24 Aryeh Jason Director Grant or award +12,422 92,482
2025-06-24 Aryeh Jason Director Grant or award · Stock Option (Right to Buy) +36,797 36,797
2025-06-24 Cleary Chris Director Grant or award +12,422 22,577
2025-06-24 Cleary Chris Director Grant or award · Stock Option (Right to Buy) +36,797 36,797

Page 5 of 16 · 314 trades