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CIK 0001814114 · Non-accelerated filer<br>Smaller reporting company

Orchestra BioMed Holdings, Inc.

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Ticker
OBIO
Exchange
Nasdaq
Industry
Surgical & Medical Instruments & Apparatus
FY end
Dec 31
Incorporated
DE
Entity type
operating
Phone
646-343-9298
Business address
150 UNION SQUARE DRIVE, NEW HOPE, PA, 18938
Former names
Health Sciences Acquisitions Corp 2
Open-market buys, last 90 days
$6,288,560
in 7 filings
Open-market sales, last 90 days
$255,600
in 3 filings, $256K under 10b5-1 plans

Net +$6,032,960. Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Date Insider Transaction Shares Price Value Owned after
2026-05-28 Sherman Darren See Remarks Shares withheld for taxes −4,925 $3.98 $20K 1,199,327
2026-05-18 Aryeh Jason Director Purchase +665 $3.75 $2K 118,118
2026-05-15 Aryeh Jason Director Purchase +8,971 $3.90 $35K 117,453
2026-05-15 Hochman David P See Remarks Purchase +5,000 $3.77 $19K 1,059,029
2026-05-14 Fain Eric S Director Purchase +20,000 $4.13 $83K 91,709
2026-04-27 RTW INVESTMENTS, LP 10% owner Option exercise +1,250,032 $0.00 $125 9,556,095
2026-04-27 RTW INVESTMENTS, LP 10% owner Sale −32 $4.13 $132 9,556,063
2026-04-27 RTW INVESTMENTS, LP 10% owner Option exercise · Pre-Funded Warrants (Right to Buy) −1,250,032 $2.75 $3.4M 2,386,331
2026-03-25 Sherman Darren See Remarks Shares withheld for taxes −33,317 $4.57 $152K 1,204,252
2026-03-25 Aiello Joshua Principal Accounting Officer Shares withheld for taxes −241 $4.57 $1K 18,644
2026-03-25 Hochman David P See Remarks Shares withheld for taxes −32,438 $4.57 $148K 1,054,029
2026-03-13 Hochman David P See Remarks Purchase +10,000 $4.29 $43K 1,086,467
2026-02-12 Aiello Joshua Principal Accounting Officer Grant or award · Stock Option (Right to Buy) +70,000 70,000
2026-02-12 Sherman Darren See Remarks Grant or award +397,000 1,237,569
2026-02-12 Taylor Andrew Lawrence Chief Financial Officer Grant or award +181,000 632,493
2026-02-12 Hochman David P See Remarks Grant or award +504,000 1,076,467
2026-02-05 Cleary Chris Director Shares withheld for taxes −676 $3.71 $3K 36,901
2026-01-28 Sherman Darren See Remarks Grant or award · Stock Option +34,974 34,974
2026-01-02 Taylor Andrew Lawrence Chief Financial Officer Shares withheld for taxes −3,452 $4.31 $15K 451,493
2026-01-02 Aiello Joshua Principal Accounting Officer Shares withheld for taxes −241 $4.31 $1K 18,885

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