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CIK 0000874015 · Large accelerated filer

IONIS PHARMACEUTICALS INC

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Ticker
IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
FY end
Dec 31
Incorporated
CA
Entity type
operating
EIN
330336973
Phone
7609319200
Business address
2855 GAZELLE COURT, CARLSBAD, CA, 92010
Former names
ISIS PHARMACEUTICALS INC
Open-market buys, last 90 days
$148,200
in 1 filing
Open-market sales, last 90 days
$61,389
in 2 filings

Net +$86,811. Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Reading 100 more Form 4s from the SEC; this list fills in as they're read.

Date Insider Transaction Shares Price Value Owned after
2026-03-10 Monia Brett P Chief Executive Officer Option exercise · Non-Qualified Stock Option (right to buy) 10b5-1 −34,103 0
2026-03-10 Jenne Kyle EVP, Chf GL Pdt Str Ofcr Option exercise 10b5-1 +32,602 $46.10 $1.5M 48,991
2026-03-10 Jenne Kyle EVP, Chf GL Pdt Str Ofcr Sale 10b5-1 −21,191 $75.50 $1.6M 27,800
2026-03-10 Jenne Kyle EVP, Chf GL Pdt Str Ofcr Sale 10b5-1 −16,086 $76.30 $1.2M 11,714
2026-03-10 Jenne Kyle EVP, Chf GL Pdt Str Ofcr Option exercise 10b5-1 +4,675 $34.69 $162K 16,389
2026-03-10 Jenne Kyle EVP, Chf GL Pdt Str Ofcr Option exercise · Non-Qualified Stock Option (right to buy) 10b5-1 −4,675 14,025
2026-03-10 Jenne Kyle EVP, Chf GL Pdt Str Ofcr Option exercise · Non-Qualified Stock Option (right to buy) 10b5-1 −32,602 32,601
2026-03-09 O'NEIL PATRICK R. EVP CLO & General Counsel Sale 10b5-1 −10,148 $75.25 $764K 62,211
2026-03-09 Monia Brett P Chief Executive Officer Option exercise 10b5-1 +40,822 $60.89 $2.5M 295,803
2026-03-09 Monia Brett P Chief Executive Officer Option exercise 10b5-1 +73,529 $60.89 $4.5M 369,332
2026-03-09 Monia Brett P Chief Executive Officer Sale 10b5-1 −7,382 $74.11 $547K 361,950
2026-03-09 Monia Brett P Chief Executive Officer Sale 10b5-1 −117,604 $75.26 $8.9M 244,346
2026-03-09 Monia Brett P Chief Executive Officer Sale 10b5-1 −1,684 $75.58 $127K 242,662
2026-03-09 Monia Brett P Chief Executive Officer Option exercise · Non-Qualified Stock Option (right to buy) 10b5-1 −40,822 107,632
2026-03-09 Monia Brett P Chief Executive Officer Option exercise · Non-Qualified Stock Option (right to buy) 10b5-1 −73,529 34,103
2026-03-04 LOSCALZO JOSEPH Director Option exercise 10b5-1 +200 $38.06 $8K 36,530
2026-03-04 LOSCALZO JOSEPH Director Sale 10b5-1 −200 $80.00 $16K 36,330
2026-03-04 LOSCALZO JOSEPH Director Option exercise · Non-Qualified Stock Option (right to buy) 10b5-1 −200 10,968
2026-03-04 Baroldi Joseph EVP, Chief Business Officer Option exercise 10b5-1 +238 $56.78 $14K 4,585
2026-03-04 Baroldi Joseph EVP, Chief Business Officer Sale 10b5-1 −238 $80.00 $19K 4,347

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