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CIK 0001714899 · Large accelerated filer

Denali Therapeutics Inc.

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Ticker
DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
FY end
Dec 31
Incorporated
DE
Entity type
operating
EIN
463872213
Phone
(650) 866-8547
Business address
161 OYSTER POINT BLVD., SOUTH SAN FRANCISCO, CA, 94080
Open-market buys, last 90 days
$0
in 0 filings
Open-market sales, last 90 days
$363,678
in 3 filings, $327K under 10b5-1 plans

Net −$363,678. Shares bought or sold at a price by officers, directors and 10% owners (Form 4 codes P and S). Grants, option exercises and tax withholding aren't counted.

Reading 8 more Form 4s from the SEC; this list fills in as they're read.

Date Insider Transaction Shares Price Value Owned after
2026-06-03 BAKER BROS. ADVISORS LP Director Grant or award · Non-Qualified Stock Option (right to buy) +19,226 19,226
2026-06-03 BAKER BROS. ADVISORS LP Director Grant or award · Non- Qualified Stock Option (right to buy) +19,226 19,226
2026-06-03 FLATLEY JAY T Director Grant or award +6,408 22,628
2026-06-03 FLATLEY JAY T Director Grant or award · Stock Option (right to buy) +19,226 19,226
2026-01-06 Schuth Alexander O. COFO and Secretary Sale −17,218 $16.50 $284K 282,828
2026-01-06 Watts Ryan J. President and CEO Sale −35,198 $16.50 $581K 296,833
2026-01-03 Schuth Alexander O. COFO and Secretary Grant or award +57,700 300,046
2026-01-03 Schuth Alexander O. COFO and Secretary Grant or award · Stock Option (right to buy) +173,100 173,100
2026-01-03 Watts Ryan J. President and CEO Grant or award +78,960 332,031
2026-01-03 Watts Ryan J. President and CEO Grant or award · Stock Option (right to buy) +236,880 236,880
2025-12-11 BAKER BROS. ADVISORS LP Director Purchase · $0.01 Prefunded Warrants +190,523 $17.49 $3.3M 2,335,469
2025-12-11 BAKER BROS. ADVISORS LP Director Purchase · $0.01 Prefunded Warrants +2,095,191 $17.49 $36.6M 25,996,310
2025-11-04 Van Hauwermeiren Timothy Director Grant or award +10,632 10,632
2025-11-04 Van Hauwermeiren Timothy Director Grant or award · Stock Option (right to buy) +31,897 31,897
2025-09-03 Watts Ryan J. President and CEO Gift −50,000 2,152,604
2025-08-13 Ho Carole Chief Medical Officer Sale 10b5-1 −806 $14.64 $12K 216,585
2025-08-12 Schuth Alexander O. COFO and Secretary Sale −2,937 $13.58 $40K 242,346
2025-08-12 Ho Carole Chief Medical Officer Sale 10b5-1 −2,937 $13.58 $40K 217,391
2025-08-05 Ho Carole Chief Medical Officer Option exercise +44,655 $0.68 $30K 220,328
2025-08-05 Ho Carole Chief Medical Officer Option exercise · Stock Option (right to buy) −44,655 62,500

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